Med Matrix functional medicine and wellness clinic

Functional Medicine in Portland, Maine

Portland residents searching for a functional medicine doctor have Med Matrix just minutes away in South Portland. We spend a full hour with every patient, run over 100 biomarkers at your first visit, and build a treatment plan around what is actually driving your symptoms. No 15-minute appointments, no guessing.

4.9 stars150+ reviews3,000+ patients7 providers

Functional Medicine Doctors Near Portland, Maine

Finding a functional medicine doctor near Portland who takes the time to listen and test thoroughly can be frustrating. Most conventional offices run a basic panel, tell you everything looks "normal," and send you on your way. At Med Matrix, we take a different approach.

Our clinic in South Portland is a short drive from downtown Portland. We run a 100-biomarker blood panel at your first visit, including a full thyroid panel (TSH, T3, T4, antibodies), hormones, metabolic markers, inflammatory markers, and more. Your provider then sits with you for a full hour to review every result and explain what is actually going on.

If you are new to functional medicine, our beginner's guide to functional medicine explains how it differs from conventional care and what to expect at your first visit.

Everything Under One Roof

Advanced testing, personalized protocols, and real results from a team that treats the whole picture.

Med Matrix clinic building in South Portland, Maine

4.9

from 150+ Google Reviews

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Holistic and Integrative Medicine in Portland

Many Portland residents search for holistic or integrative medicine because they want a provider who looks at the whole person, not just individual symptoms. That is exactly what functional medicine does. We look at how your hormones, thyroid, gut health, metabolism, and inflammation all connect to the way you feel.

A common example: a patient comes in with fatigue, weight gain, and brain fog. Their PCP checked TSH and said thyroid was "fine." At Med Matrix, we check TSH, free T3, free T4, and thyroid antibodies. We also check cortisol, insulin, vitamin D, and hormone levels. The root cause often shows up in the markers that were never tested.

We have 7 providers on staff, all trained in functional medicine, and we have served over 3,000 patients. Our podcast on functional medicine covers the philosophy behind our approach and what makes it different from conventional care.

Where Your Providers Train

Functional medicine isn't taught in medical school. Our providers invest years of additional training with the institutions that built this field.

Institute for Functional Medicine logo

Institute for Functional Medicine(IFM)

The academic home of functional medicine. IFMCP certification requires advanced training in hormonal, immune, gastrointestinal, and neuroendocrine systems. Multiple Med Matrix providers hold this credential.

Your provider sees how your hormones, gut, immune system, and metabolism connect, not just isolated symptoms.

Seeds Scientific Research & Performance logo

Seeds Scientific Research & Performance(SSRP)

Clinical training in hormone dosing, advanced lab interpretation, and peptide protocols. Where textbook medicine gets translated into treatment plans that show measurable change inside 90 days.

Your protocol is built on real clinical training, not a one-size-fits-all template.

American Academy of Anti-Aging Medicine logo

American Academy of Anti-Aging Medicine(A4M)

The largest training body for age-management and longevity medicine. Fellowship and board certification cover hormone replacement, peptide therapy, metabolic medicine, and regenerative therapies.

Your care team trains with the organization that sets the clinical standard for longevity medicine.

See the full credentials and training history of every provider in our free practice guide.

Advanced Lab Testing in Portland, Maine

Lab testing is the foundation of everything we do. Unlike a standard physical where you get a basic metabolic panel and a CBC, our testing covers over 100 biomarkers. This includes thyroid function, sex hormones, adrenal markers, inflammatory markers, metabolic health, nutrient levels, and more.

We also perform an InBody 770 body composition scan to measure your muscle mass, body fat, and hydration levels. This gives your provider a full baseline to track your progress over time.

Portland patients regularly tell us they have never had this level of testing done before. That is not surprising. Insurance-based medicine limits what your conventional doctor can order. Our providers are not constrained by those limitations. Learn more in our guide to advanced bloodwork.

Advanced Diagnostics Beyond the Standard Panel

If the standard panel doesn't explain how you feel, there's usually a reason hiding deeper. Functional medicine means having the tools to find it. These are some of the advanced tests your provider can add when the initial results point to something that needs more investigation.

DUTCH Complete

What it measures: Dried urine panel of every sex hormone metabolite plus cortisol rhythm.

Why we use it: Serum hormones are a snapshot. DUTCH shows the full metabolic picture over a day, including how you process hormones and whether your stress system is burning out.

GI-MAP

What it measures: PCR-based stool test for pathogens, parasites, yeast overgrowth, and microbiome balance.

Why we use it: Most chronic gut issues trace back to one of four places. GI-MAP tells us which, so treatment targets the actual cause.

SIBO Breath Test

What it measures: Hydrogen and methane gas after a sugar challenge, flagging bacterial overgrowth in the small intestine.

Why we use it: SIBO is treated completely differently from large-intestine dysbiosis. Getting the diagnosis right changes everything.

Mycotoxin Screening

What it measures: Urine panel for the specific toxins produced by mold.

Why we use it: Mold toxicity looks like twenty other conditions. Until you rule it out, you won't find the real cause.

Heavy Metals Testing

What it measures: Urine or blood panel for lead, mercury, arsenic, cadmium, and other toxic metals.

Why we use it: Heavy metal burden accumulates for years without symptoms, then drives neurologic or autoimmune issues that standard panels never catch.

Our practice guide includes the full catalog of advanced testing options with detailed descriptions of what each one measures. Get your free copy.

Serving Portland, Maine

Take the First Step

Get your free practice guide and a $100 voucher toward your first visit. No commitment required.

1Download your free guide
2Claim your $100 voucher
3Book your consultation
Free practice guide and $100 voucher toward your first functional medicine visit

Free Practice Guide + $100 Voucher

Everything you need before your first visit

STEP 1 OF 3

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We only accept a limited number of patients per week

Insights from Our Podcast

Our providers break down the science behind your health concerns and what you can do about them.

Med Matrix Podcast: Is Your Thyroid Actually Fine? Why TSH Alone Misses 90% of Hypothyroid Root Causes

Is Your Thyroid Actually Fine? Why TSH Alone Misses 90% of Hypothyroid Root Causes

Colin Renaud, PA-C walks through the thyroid in depth, covering why it is one of the most under-managed conditions in conventional medicine, how the gut directly affects thyroid hormone conversion, why Hashimoto's (autoimmune thyroid disease) is the root cause of roughly 90% of hypothyroidism in the US, and what a complete functional medicine thyroid workup actually looks at compared to the single TSH test most patients receive. The episode includes a myth-or-fact rapid-fire segment, a case study of a patient whose antibody levels nearly halved after going gluten-free, and a live Q&A covering ANA antibodies, fecal transplants, and whether thyroid problems are ever reversible. The central message is that treating only TSH with levothyroxine while ignoring antibodies, conversion, gut health, and nutrition is a major failure of the standard model.

Watch Episode →
Med Matrix Podcast: Why Am I So Tired All the Time? The Root Causes Your Doctor Is Missing

Why Am I So Tired All the Time? The Root Causes Your Doctor Is Missing

Cole Siefer and Colin Renaud DC, PA-C dig into the root causes of chronic fatigue, explaining why patients are so often dismissed with "you're just getting older" or "you're a busy mom." The episode covers the cellular biology of energy production (ATP, mitochondria, B vitamins, magnesium), the connection between sex hormones and energy, how gut dysfunction diverts energy away from normal body functions, and why thyroid optimization goes far beyond a standard TSH test. The conversation ends with a case study of a high-performing man in his late 30s who recovered his energy within days of addressing hormone deficiencies.

Watch Episode →
Med Matrix Podcast: Why You Can't Sleep Through the Night: Hormones, Gut Health, and the Science of Deep Sleep

Why You Can't Sleep Through the Night: Hormones, Gut Health, and the Science of Deep Sleep

Colin Renaud, PA-C breaks down the science of sleep from a functional medicine perspective, covering why sleep is the body's nightly repair cycle, what disrupts it, and how to fix it without defaulting to prescription sleep aids. The episode moves through sleep physiology, sleep hygiene (nutrition, screens, temperature, schedule), supplement guidance, sleep apnea, hormone connections to sleep, and gut health's role in melatonin and serotonin production. Case studies include menopausal women whose sleep transformed with hormone replacement and patients with nervous system hyperarousal. The episode closes with a listener Q&A and a sleep gadget ranking game.

Watch Episode →
Med Matrix Podcast: Why Your Lyme Test Was Wrong: FISH Testing, Co-Infections, and What Conventional Medicine Misses

Why Your Lyme Test Was Wrong: FISH Testing, Co-Infections, and What Conventional Medicine Misses

Cole Siefer hosts Dr. Sasha Rose and Colin Renaud (DC, PA-C) for an in-depth webinar on Lyme disease and tick-borne illness. The episode covers why Lyme is so frequently missed or misdiagnosed in conventional medicine, the critical limitations of standard Western blot and ELISA testing, and why FISH (fluorescent microscopy) testing is the gold standard but remains inaccessible to most patients. The providers explain co-infections (Bartonella, Babesia) as often more debilitating than Lyme itself, share two patient case studies (both involving young women who eventually recovered over months to years), and close with a myth-busting rapid-fire round debunking 15 common Lyme misconceptions. Colin Renaud (DC, PA-C) is a member of ILADS (International Lyme and Associated Diseases Society) and has spoken at their conferences.

Watch Episode →

How It Works

Your path to feeling like yourself again, step by step.

01.

Free Discovery Call

  • Talk with our patient coordinator about your goals, symptoms, and concerns
  • Understand your options and what to expect
  • Get matched with the right provider for your needs

Result: A clear next step personalized to your situation, with no pressure or commitment.

02.

80+ Biomarker Test & Full Body Scan

  • Comprehensive panel of 80+ lab markers
  • Full body composition scan
  • In-depth health questionnaires

Result: A complete picture of your health, so nothing gets missed.

03.

Medical Team Reviews Everything

  • Providers review your labs, medical history, and questionnaires
  • Cross-reference symptoms with biomarker patterns
  • Identify root causes, not just surface symptoms

Result: A personalized treatment plan built from real data, not guesswork.

04.

60-Minute Provider Consultation

  • Sit down with your provider for a full hour
  • Go over every result in detail
  • Build your personalized plan together

Result: You leave with a clear understanding of what is happening and exactly what to do about it.

05.

Ongoing Support & Progress

  • Continued monitoring of your labs and markers
  • Adjustments to your plan as your body responds
  • Direct access to your care team

Result: Real, measurable progress you can feel and see in your numbers.

Start Here

Med Matrix - Functional Medicine and Medspa

Address

198 Maine Mall Road
South Portland, ME 04106

Get Directions →

Phone

(207) 544-4643

Serving Portland and surrounding areas

Hours

Mon: 8:00 AM - 4:00 PM

Tue: 9:00 AM - 5:00 PM

Wed: 8:00 AM - 4:00 PM

Thu: 9:00 AM - 5:00 PM

Fri: 8:00 AM - 3:00 PM

Sat: Closed

Sun: Closed

Functional Medicine in Portland

Common questions about functional medicine near Portland, Maine.

Med Matrix is located in South Portland, just a few minutes from downtown Portland. The clinic is easily accessible from the Maine Mall area.

Your first visit includes a 100-biomarker blood panel, an InBody 770 body composition scan, and a one-hour consultation with your provider. They review every result with you and build a personalized treatment plan.

Your first visit is $100 with our current voucher. The full onboarding, including labs, body composition scan, and a one-hour provider consultation, is approximately $1,200 to $1,500. Follow-up visits are $275. We accept HSA, FSA, CareCredit, and all major cards.

Med Matrix is a cash-pay clinic. This allows our providers to spend a full hour with you and order the advanced testing that insurance-based practices cannot. We accept HSA, FSA, CareCredit, and all major credit cards.

We work with patients dealing with fatigue, thyroid issues, hormone imbalances, gut problems, autoimmune conditions, brain fog, chronic pain, weight that will not budge, and more. Our approach is to find the root cause rather than manage symptoms with medication alone.

Conventional medicine is designed to diagnose disease and prescribe medication. Functional medicine looks at why you feel the way you do, even when your standard labs come back normal. We test deeper, spend more time, and build a plan around your individual biology.

Free practice guide and $100 voucher for functional medicine consultation at Med Matrix

Start Feeling Like Yourself Again

Get your free practice guide and a $100 voucher. Your first step toward real answers starts here.